Extracellular vesicles derived from induced pluripotent stem cells mediate anti-inflammatory effects in primary human macrophages

Abstract Extracellular vesicles derived from induced pluripotent stem cells (iPSC EVs) have immunoregulatory potential with the ability to alter the macrophage phenotype. Modulating the macrophage phenotype towards an anti-inflammatory, pro-resolving state may be beneficial in the treatment of chron...

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Bibliografiske detaljer

Principais autores:	Stephen Fitzsimons, Silvia Oggero, Billy P. Egan, Eugène T. Dillon, María Muñoz-San Martín, Shane Clerkin, Ciarán Kennedy, Jessica Davis, Darrell Andrews, John Crean, Orina Belton
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Portfolio 2026-05-01
Serier:	Scientific Reports
Fag:	Extracellular vesicles iPSCs Macrophages Monocytes Inflammation
Online adgang:	https://doi.org/10.1038/s41598-026-49621-w
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