Calnuc plays a role in dynamic distribution of Gαi but not Gβ subunits and modulates ACTH secretion in AtT-20 neuroendocrine secretory cells
<p>Abstract</p> <p>In AtT-20 cells ACTH secretion is regulated by both Ca<sup>2+ </sup>and G proteins. We previously demonstrated that calnuc, an EF-hand Ca<sup>2+ </sup>binding protein which regulates Alzheimer's β-amyloid precursor protein (APP) biogenesis, binds both Ca<sup>2+ </sup>as well as Gα...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BMC
2009-03-01
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| Colección: | Molecular Neurodegeneration |
| Acceso en línea: | http://www.molecularneurodegeneration.com/content/4/1/15 |
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