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Strontium Binding to α-Parvalbumin, a Canonical Calcium-Binding Protein of the “EF-Hand” Family

Strontium salts are used for treatment of osteoporosis and bone cancer, but their impact on calcium-mediated physiological processes remains obscure. To explore Sr<sup>2+</sup> interference with Ca<sup>2+</sup> binding to proteins of the EF-hand family, we studied Sr<sup>2+</sup>/Ca<sup>2+</sup> int...

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Автори: Alisa A. Vologzhannikova, Marina P. Shevelyova, Alexey S. Kazakov, Andrey S. Sokolov, Nadezhda I. Borisova, Eugene A. Permyakov, Nikoleta Kircheva, Valya Nikolova, Todor Dudev, Sergei E. Permyakov
Формат: Artigo
Мова:Inglês
Опубліковано: MDPI AG 2021-08-01
Серія:Biomolecules
Предмети:
metal selectivity
calcium-binding proteins
EF-hand
parvalbumin
protein structure
protein stability
Онлайн доступ:https://www.mdpi.com/2218-273X/11/8/1158
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