Simultaneous profiling of RNA isoforms and chromatin accessibility of single cells of human retinal organoids

Abstract Single-cell multi-omics sequencing is a powerful approach to analyze complex mechanisms underlying neuronal development and regeneration. However, current methods lack the ability to simultaneously profile RNA alternative splicing and chromatin accessibility at the single-cell level. We dev...

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Hlavní autoři:	Shuyao Zhang, Yuhua Xiao, Xinzhi Mo, Xu Chen, Jiawei Zhong, Zheyao Chen, Xu Liu, Yuanhui Qiu, Wangxuan Dai, Jia Chen, Xishan Jin, Guoping Fan, Youjin Hu
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2024-09-01
Edice:	Nature Communications
On-line přístup:	https://doi.org/10.1038/s41467-024-52335-0
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