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Parental Origin of Gsα Inactivation Differentially Affects Bone Remodeling in a Mouse Model of Albright Hereditary Osteodystrophy

ABSTRACT Albright hereditary osteodystrophy (AHO) is caused by heterozygous inactivation of GNAS, a complex locus that encodes the alpha‐stimulatory subunit of heterotrimeric G proteins (Gsα) in addition to NESP55 and XLαs due to alternative first exons. AHO skeletal manifestations include brachydac...

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Váldodahkkit: Patrick McMullan, Peter Maye, Qingfen Yang, David W. Rowe, Emily L. Germain‐Lee
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Oxford University Press 2022-01-01
Ráidu:JBMR Plus
Fáttát:
Liŋkkat:https://doi.org/10.1002/jbm4.10570
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