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Purified Serum IgG from a Patient with Anti-IgLON5 Antibody Cause Long-Term Movement Disorders with Impaired Dopaminergic Pathways in Mice

<b>Background</b>: Anti-IgLON5 disease is a rare autoimmune disease of the central nervous system. It typically manifests as a chronic condition, characterized by cognitive impairments, movement disorders, and sleep disorders. The mechanisms underlying movement disorders in this disease remain poorl...

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Autori principali: Yining Gao, Hongxia Li, Huoqing Luo, You Ni, Yifan Feng, Lu He, Qinming Zhou, Ji Hu, Sheng Chen
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2023-09-01
Serie:Biomedicines
Soggetti:
anti-IgLON5 disease
movement disorders
neuropathology
dopaminergic pathways
substantia nigra pars compacta
Accesso online:https://www.mdpi.com/2227-9059/11/9/2483
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