Hybridization Properties of RNA Containing 8-Methoxyguanosine and 8-Benzyloxyguanosine.

Modified nucleobase analogues can serve as powerful tools for changing physicochemical and biological properties of DNA or RNA. Guanosine derivatives containing bulky substituents at 8 position are known to adopt syn conformation of N-glycoside bond. On the contrary, in RNA the anti conformation is...

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Главные авторы:	Daniel Sylwester Baranowski, Weronika Kotkowiak, Ryszard Kierzek, Anna Pasternak
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Public Library of Science (PLoS) 2015-01-01
Серии:	PLoS ONE
Online-ссылка:	http://europepmc.org/articles/PMC4564172?pdf=render
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