RETRACTED ARTICLE: Epidermal growth factor-receptor activation modulates Src-dependent resistance to lapatinib in breast cancer models

Abstract Introduction Src tyrosine kinase overactivation has been correlated with a poor response to human epidermal growth factor receptor 2 (HER2) inhibitors in breast cancer. To identify the mechanism by which Src overexpression sustains this resistance, we tested a panel of breast cancer cell li...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Luigi Formisano, Lucia Nappi, Roberta Rosa, Roberta Marciano, Claudia D’Amato, Valentina D’Amato, Vincenzo Damiano, Lucia Raimondo, Francesca Iommelli, Antonella Scorziello, Giancarlo Troncone, Bianca Maria Veneziani, Sarah J Parsons, Sabino De Placido, Roberto Bianco
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2014-05-01
coleção:	Breast Cancer Research
Assuntos:	Epidermal Growth Factor Receptor Cetuximab Focal Adhesion Kinase Lapatinib Epidermal Growth Factor Receptor Activation
Acesso em linha:	https://doi.org/10.1186/bcr3650
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!