RETRACTED ARTICLE: Epidermal growth factor-receptor activation modulates Src-dependent resistance to lapatinib in breast cancer models

Abstract Introduction Src tyrosine kinase overactivation has been correlated with a poor response to human epidermal growth factor receptor 2 (HER2) inhibitors in breast cancer. To identify the mechanism by which Src overexpression sustains this resistance, we tested a panel of breast cancer cell li...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Luigi Formisano, Lucia Nappi, Roberta Rosa, Roberta Marciano, Claudia D’Amato, Valentina D’Amato, Vincenzo Damiano, Lucia Raimondo, Francesca Iommelli, Antonella Scorziello, Giancarlo Troncone, Bianca Maria Veneziani, Sarah J Parsons, Sabino De Placido, Roberto Bianco
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2014-05-01
Schriftenreihe:	Breast Cancer Research
Schlagworte:	Epidermal Growth Factor Receptor Cetuximab Focal Adhesion Kinase Lapatinib Epidermal Growth Factor Receptor Activation
Online-Zugang:	https://doi.org/10.1186/bcr3650
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