Sipa1 deficiency–induced bone marrow niche alterations lead to the initiation of myeloproliferative neoplasm
Abstract: Mutations of signal-induced proliferation-associated gene 1 (SIPA1), a RAP1 GTPase-activating protein, were reported in patients with juvenile myelomonocytic leukemia, a childhood myelodysplastic/myeloproliferative neoplasm (MDS/MPN). Sipa1 deficiency in mice leads to the development of ag...
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| Główni autorzy: | , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Elsevier
2018-03-01
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| Seria: | Blood Advances |
| Dostęp online: | http://www.sciencedirect.com/science/article/pii/S2473952920310776 |
| Etykiety: |
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