AMBN mutations causing hypoplastic amelogenesis imperfecta and Ambn knockout‐NLS‐lacZ knockin mice exhibiting failed amelogenesis and Ambn tissue‐specificity

Abstract Background Ameloblastin (AMBN) is a secreted matrix protein that is critical for the formation of dental enamel and is enamel‐specific with respect to its essential functions. Biallelic AMBN defects cause non‐syndromic autosomal recessive amelogenesis imperfecta. Homozygous Ambn mutant mice...

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Detalhes bibliográficos

Principais autores:	Tian Liang, Yuanyuan Hu, Charles E. Smith, Amelia S Richardson, Hong Zhang, Jie Yang, Brent Lin, Shih‐Kai Wang, Jung‐Wook Kim, Yong‐Hee Chun, James P. Simmer, Jan C.‐C. Hu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2019-09-01
coleção:	Molecular Genetics & Genomic Medicine
Assuntos:	Ambn ‐/‐ Amelx ‐/- amelin ameloblastin amelogenin dental enamel formation matrix proteins
Acesso em linha:	https://doi.org/10.1002/mgg3.929
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