Overexpression of TBX3 suppresses tumorigenesis in experimental and human cholangiocarcinoma

Abstract TBX3 behaves as a tumor suppressor or oncoprotein across cancer. However, TBX3 function remains undetermined in intrahepatic cholangiocarcinoma (iCCA), a deadly primary liver malignancy with few systemic treatment options. This study sought to investigate the impact of TBX3 on iCCA. We foun...

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Bibliografski detalji

Glavni autori:	Shanshan Deng, Xinjun Lu, Xue Wang, Binyong Liang, Hongwei Xu, Doris Yang, Guofei Cui, Andrew Yonemura, Honor Paine, Yi Zhou, Yi Zhang, Maria Maddalena Simile, Francesco Urigo, Matthias Evert, Diego F. Calvisi, Benjamin L. Green, Xin Chen
Format:	Artigo
Jezik:	Inglês
Izdano:	Nature Publishing Group 2024-06-01
Serija:	Cell Death and Disease
Online pristup:	https://doi.org/10.1038/s41419-024-06839-8
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