Overexpression of TBX3 suppresses tumorigenesis in experimental and human cholangiocarcinoma

Abstract TBX3 behaves as a tumor suppressor or oncoprotein across cancer. However, TBX3 function remains undetermined in intrahepatic cholangiocarcinoma (iCCA), a deadly primary liver malignancy with few systemic treatment options. This study sought to investigate the impact of TBX3 on iCCA. We foun...

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Detalles Bibliográficos

Principais autores:	Shanshan Deng, Xinjun Lu, Xue Wang, Binyong Liang, Hongwei Xu, Doris Yang, Guofei Cui, Andrew Yonemura, Honor Paine, Yi Zhou, Yi Zhang, Maria Maddalena Simile, Francesco Urigo, Matthias Evert, Diego F. Calvisi, Benjamin L. Green, Xin Chen
Formato:	Artigo
Idioma:	Inglês
Publicado:	Nature Publishing Group 2024-06-01
Series:	Cell Death and Disease
Acceso en liña:	https://doi.org/10.1038/s41419-024-06839-8
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