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Integration of single-cell RNA sequencing and bulk RNA sequencing to reveal an immunogenic cell death-related 5-gene panel as a prognostic model for osteosarcoma

BackgroundDespite the comparatively low prevalence of osteosarcoma (OS) compared to other cancer types, metastatic OS has a poor overall survival rate of fewer than 30%. Accumulating data has shown the crucial functions of immunogenic cell death (ICD) in various cancers; nevertheless, the relationsh...

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Principais autores: Jiaqi Yang, Jian Zhang, Song Na, Zhizhou Wang, Hanshuo Li, Yuxin Su, Li Ji, Xin Tang, Jun Yang, Lu Xu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-09-01
coleção:Frontiers in Immunology
Assuntos:
osteosarcoma
immunogenic cell death
prognostic panel
molecular subtype
single cell RNA sequencing
bulk RNA sequencing
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2022.994034/full
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