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Single-cell RNA sequencing reveals the immune microenvironment landscape of osteosarcoma before and after chemotherapy

Chemotherapy, a primary treatment for osteosarcoma (OS), has limited knowledge regarding its impact on tumor immune microenvironment (TIME). Here, tissues from 6 chemotherapy-naive OS patients underwent single-cell RNA sequencing (scRNA-seq) and were analyzed alongside public dataset (GSE152048) con...

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Principais autores: Yun Liu, Yunhua Lin, Shijie Liao, Wenyu Feng, Jianhong Liu, Xiaoting Luo, Qingjun Wei, Haijun Tang
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2024-01-01
coleção:Heliyon
Assuntos:
Osteosarcoma
Chemotherapy
Tumor immune microenvironment
Single-cell RNA sequencing
Heterogeneity
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2405844023108097
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