Stereoselective Block of hERG Channel by Bupivacaine Scrutinized at Molecular Level
In the heart, the hERG voltage-gated potassium channel mediates the IKr current, which is crucial for the duration of cardiac action potential. Undesired block of the channel may prolong the QT interval with increased risk of malignant ventricular arrhythmia called torsades de pointes. Alt...
Guardat en:
| Autors principals: | , , |
|---|---|
| Format: | Artigo |
| Idioma: | Alemão |
| Publicat: |
Swiss Chemical Society
2010-03-01
|
| Col·lecció: | CHIMIA |
| Matèries: | |
| Accés en línia: | https://www.chimia.ch/chimia/article/view/4821 |
| Etiquetes: |
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|