Enhanced immunogenicity of a functional enzyme by T cell epitope modification
<p>Abstract</p> <p>Background</p> <p>T helper epitopes are necessary for the induction of high titers of antigen-specific IgG antibodies. We are interested in the epitope modification of intact proteins as a method to enhance their immunogenicity for the generation of recombinant protein-based vacci...
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| Principais autores: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2002-01-01
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| coleção: | BMC Immunology |
| Acesso em linha: | http://www.biomedcentral.com/1471-2172/3/2 |
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