Benzonate derivatives of acetophenone as potent α-glucosidase inhibitors: synthesis, structure–activity relationship and mechanism
In this article, 23 compounds (6 and 7a–7v) were prepared and evaluated for their in vitro α-glucosidase inhibitory activity. The compounds 7d, 7f, 7i, 7n, 7o, 7r, 7s, 7u, and 7v displayed the α-glucosidase inhibition activity with IC50 values ranging from 1.68 to 7.88 µM. Among all tested compounds...
Na minha lista:
| Principais autores: | , , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis Group
2019-01-01
|
| Serier: | Journal of Enzyme Inhibition and Medicinal Chemistry |
| Fag: | |
| Online adgang: | http://dx.doi.org/10.1080/14756366.2019.1604519 |
| Tags: |
Ingen Tags, Vær først til at tagge denne postø!
|