Design, Synthesis, and Activity Evaluation of Novel <i>N</i>-benzyl Deoxynojirimycin Derivatives for Use as α-Glucosidase Inhibitors

To obtain &#945;-glucosidase inhibitors with high activity, 19 NB-DNJDs (<i>N</i>-benzyl-deoxynojirimycin derivatives) were designed and synthesized. The results indicated that the 19 NB-DNJDs displayed different inhibitory activities towards &#945;-glucosidase in vitro. Compound <b>18a</b> (1-(4-hy...

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المؤلفون الرئيسيون:	Fanxin Zeng, Zhongping Yin, Jiguang Chen, Xuliang Nie, Ping Lin, Tao Lu, Meng Wang, Dayong Peng
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	MDPI AG 2019-09-01
سلاسل:	Molecules
الموضوعات:	<i>N</i>-benzyl deoxynojirimycin derivatives α-glucosidase inhibitor structure-activity analysis molecular docking
الوصول للمادة أونلاين:	https://www.mdpi.com/1420-3049/24/18/3309
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!