Structure and Function of Hoc—A Novel Environment Sensing Device Encoded by T4 and Other Bacteriophages

Bacteriophage T4 is decorated with 155 180 Å-long fibers of the highly antigenic outer capsid protein (Hoc). In this study, we describe a near-atomic structural model of Hoc by combining cryo-electron microscopy and AlphaFold structure predictions. It consists of a conserved C-terminal capsid-bindin...

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Manylion Llyfryddiaeth

Prif Awduron:	Andrei Fokine, Mohammad Zahidul Islam, Qianglin Fang, Zhenguo Chen, Lei Sun, Venigalla B. Rao
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	MDPI AG 2023-07-01
Cyfres:	Viruses
Pynciau:	bacteriophage T4 phage head structure highly immunogenic outer capsid protein Hoc capsid decoration protein phage display antigen display
Mynediad Ar-lein:	https://www.mdpi.com/1999-4915/15/7/1517
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!