Structure and Function of Hoc—A Novel Environment Sensing Device Encoded by T4 and Other Bacteriophages

Bacteriophage T4 is decorated with 155 180 Å-long fibers of the highly antigenic outer capsid protein (Hoc). In this study, we describe a near-atomic structural model of Hoc by combining cryo-electron microscopy and AlphaFold structure predictions. It consists of a conserved C-terminal capsid-bindin...

Popoln opis

Bibliografske podrobnosti

Principais autores:	Andrei Fokine, Mohammad Zahidul Islam, Qianglin Fang, Zhenguo Chen, Lei Sun, Venigalla B. Rao
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2023-07-01
Serija:	Viruses
Teme:	bacteriophage T4 phage head structure highly immunogenic outer capsid protein Hoc capsid decoration protein phage display antigen display
Online dostop:	https://www.mdpi.com/1999-4915/15/7/1517
Oznake:	Označite Brez oznak, prvi označite!