Human Mitochondrial DNA Polymerase Metal Dependent UV Lesion Bypassing Ability
Human mitochondrial DNA contains more UV-induced lesions than the nuclear DNA due to lack of mechanism to remove bulky photoproducts. Human DNA polymerase gamma (Pol γ) is the sole DNA replicase in mitochondria, which contains a polymerase (pol) and an exonuclease (exo) active site. Previous studies...
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| Автори: | , , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Frontiers Media S.A.
2022-03-01
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| Серія: | Frontiers in Molecular Biosciences |
| Предмети: | |
| Онлайн доступ: | https://www.frontiersin.org/articles/10.3389/fmolb.2022.808036/full |
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