Human Mitochondrial DNA Polymerase Metal Dependent UV Lesion Bypassing Ability
Human mitochondrial DNA contains more UV-induced lesions than the nuclear DNA due to lack of mechanism to remove bulky photoproducts. Human DNA polymerase gamma (Pol γ) is the sole DNA replicase in mitochondria, which contains a polymerase (pol) and an exonuclease (exo) active site. Previous studies...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
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Frontiers Media S.A.
2022-03-01
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| Edice: | Frontiers in Molecular Biosciences |
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| On-line přístup: | https://www.frontiersin.org/articles/10.3389/fmolb.2022.808036/full |
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