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Unraveling the Structure of Meclizine Dihydrochloride with MicroED

Abstract Meclizine (Antivert, Bonine) is a first‐generation H1 antihistamine used in the treatment of motion sickness and vertigo. Despite its wide medical use for over 70 years, its crystal structure and the details of protein‐drug interactions remained unknown. Single‐crystal X‐ray diffraction (SC...

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書誌詳細
主要な著者: Jieye Lin, Johan Unge, Tamir Gonen
フォーマット: Artigo
言語:Inglês
出版事項: Wiley 2024-02-01
シリーズ:Advanced Science
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オンライン・アクセス:https://doi.org/10.1002/advs.202306435
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