Myc controls NK cell development, IL-15-driven expansion, and translational machinery

Myc ablation in vivo impacts immature NK cells’ ribosomagenesis and development. Accordingly, mice with NK cells lacking Myc exhibit impaired anticancer immunity. MYC is a pleiotropic transcription factor involved in cancer, cell proliferation, and metabolism. Its regulation and function in NK cells...

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Hlavní autoři:	Hanif J Khameneh, Nicolas Fonta, Alessandro Zenobi, Charlène Niogret, Pedro Ventura, Concetta Guerra, Ivo Kwee, Andrea Rinaldi, Matteo Pecoraro, Roger Geiger, Andrea Cavalli, Francesco Bertoni, Eric Vivier, Andreas Trumpp, Greta Guarda
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Life Science Alliance LLC 2023-07-01
Edice:	Life Science Alliance
On-line přístup:	https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202302069
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