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Leukemic stem cells and therapy resistance in acute myeloid leukemia

A major obstacle in the treatment of acute myeloid leukemia (AML) is refractory disease or relapse after achieving remission. The latter arises from a few therapy-resistant cells within minimal residual disease (MRD). Resistant cells with long-term self-renewal capacity that drive clonal outgrowth...

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Hlavní autoři: Patrick Stelmach, Andreas Trumpp
Médium: Artigo
Jazyk:Inglês
Vydáno: Ferrata Storti Foundation 2023-02-01
Edice:Haematologica
On-line přístup:https://haematologica.org/article/view/10948
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