Mitochondrial Dysfunctions Contribute to Hypertrophic Cardiomyopathy in Patient iPSC-Derived Cardiomyocytes with MT-RNR2 Mutation

Summary: Hypertrophic cardiomyopathy (HCM) is the most common cause of sudden cardiac death in young individuals. A potential role of mtDNA mutations in HCM is known. However, the underlying molecular mechanisms linking mtDNA mutations to HCM remain poorly understood due to lack of cell and animal m...

Fuld beskrivelse

Bibliografiske detaljer

Principais autores:	Shishi Li, Huaye Pan, Chao Tan, Yaping Sun, Yanrui Song, Xuan Zhang, Wei Yang, Xuexiang Wang, Dan Li, Yu Dai, Qiang Ma, Chenming Xu, Xufen Zhu, Lijun Kang, Yong Fu, Xuejun Xu, Jing Shu, Naiming Zhou, Feng Han, Dajiang Qin, Wendong Huang, Zhong Liu, Qingfeng Yan
Format:	Artigo
Sprog:	Inglês
Udgivet:	Elsevier 2018-03-01
Serier:	Stem Cell Reports
Online adgang:	http://www.sciencedirect.com/science/article/pii/S2213671118300390
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!