Disruption of the Opal Stop Codon Attenuates Chikungunya Virus-Induced Arthritis and Pathology

ABSTRACT Chikungunya virus (CHIKV) is a mosquito-borne alphavirus responsible for several significant outbreaks of debilitating acute and chronic arthritis and arthralgia over the past decade. These include a recent outbreak in the Caribbean islands and the Americas that caused more than 1 million c...

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Prif Awduron:	Jennifer E. Jones, Kristin M. Long, Alan C. Whitmore, Wes Sanders, Lance R. Thurlow, Julia A. Brown, Clayton R. Morrison, Heather Vincent, Kayla M. Peck, Christian Browning, Nathaniel Moorman, Jean K. Lim, Mark T. Heise
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	American Society for Microbiology 2017-12-01
Cyfres:	mBio
Pynciau:	alphavirus chikungunya opal stop codon viral pathogenesis
Mynediad Ar-lein:	https://journals.asm.org/doi/10.1128/mBio.01456-17
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