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Investigating the causal relationship between ankylosing spondylitis and osteoporosis in the European population: a bidirectional Mendelian randomization study

BackgroundAnkylosing Spondylitis (AS) is an inflammatory condition affecting the spine, which may lead to complications such as osteoporosis (OP). Many observational studies have demonstrated a close relationship with strong evidence between OP and AS. The combination of AS and OP is already an indi...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Jian Mei, Hongxin Hu, Haiqi Ding, Ying Huang, Wenming Zhang, Xiaoqing Chen, Xinyu Fang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2023-06-01
Schriftenreihe:Frontiers in Immunology
Schlagworte:
Mendelian randomization
ankylosing spondylitis
osteoporosis
bone mineral density
single nucleotide polymorphisms
GWAS
Online-Zugang:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1163258/full
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