Causal relationship between Interleukin-27 expression levels and osteoporosis: a bidirectional mendelian randomization study

Abstract Background This study aimed to evaluate the causal relationship between Interleukin-27 (IL-27) and osteoporosis by bidirectional Mendelian randomization (MR) analysis. Methods Firstly, the genome-wide association study summary data of osteoporosis (finn-b-M13_OSTEOPOROSIS) and IL-27 levels...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Yun Xue, You Zhou, Chunyan Li, Jingshuang Zhang, Fei Liu, Rui Shi
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2024-08-01
Schriftenreihe:	BMC Musculoskeletal Disorders
Schlagworte:	Osteoporosis Interleukin-27 Mendelian randomization Causality Enrichment analysis
Online-Zugang:	https://doi.org/10.1186/s12891-024-07765-8
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!