Coactivation of CB1 and GPR55 promotes GABA release and motor behavior at striatonigral terminals through increased dimerization induced by CB1 activation

CB1 and GPR55 receptors form heteromers in striatal neurons; however, the effects of these heteromers on GABA release at their terminals and their impact on motor behavior remain unknown. In this study, we investigate the presence of CB1-GPR55 heteromers on striatonigral neurons and their axon termi...

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Detalles Bibliográficos

Principais autores:	José Arturo Avalos-Fuentes, Rodolfo Sánchez-Zavaleta, Ihosvany Rodríguez Pérez, Rafael Jijón-Lorenzo, Refugio Cruz-Trujillo, María Fernanda González de la Torre, Martha Abigail Villareal Zuñiga, Benjamín Florán
Formato:	Artigo
Idioma:	Inglês
Publicado:	Frontiers Media S.A. 2026-02-01
Series:	Frontiers in Molecular Neuroscience
Assuntos:	CB1 receptor GPR55 heteromers motor behavior substantia nigra
Acceso en liña:	https://www.frontiersin.org/articles/10.3389/fnmol.2026.1717829/full
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