Targeting CD276 by CAR-T cells induces regression of esophagus squamous cell carcinoma in xenograft mouse models

Esophageal cancer, including esophageal squamous cell carcinoma (ESCC) and esophageal adenocarcinoma (EAC), has a poor prognosis and limited therapeutic options. Chimeric antigen receptor (CAR)-T cells represent a potential ESCC treatment. In this study, we examined CD276 expression in healthy and e...

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Xehetasun bibliografikoak

Egile Nagusiak:	Yujing Xuan, Yuqiao Sheng, Daiqun Zhang, Kai Zhang, Zhen Zhang, Yu Ping, Shumin Wang, Xiaojuan Shi, Jingyao Lian, Kangdong Liu, Yi Zhang, Feng Li
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Elsevier 2021-08-01
Saila:	Translational Oncology
Gaiak:	Esophageal cancer CD276 CAR-T cell Co-stimulation Patient-derived xenograft
Sarrera elektronikoa:	http://www.sciencedirect.com/science/article/pii/S1936523321001303
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