Natural killer cell activation by respiratory syncytial virus‐specific antibodies is decreased in infants with severe respiratory infections and correlates with Fc‐glycosylation

Abstract Objectives Respiratory syncytial virus (RSV) is a major cause of severe lower respiratory tract infections in infants, and there is no vaccine available. In early life, the most important contributors to protection against infectious diseases are the innate immune response and maternal anti...

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Detalhes bibliográficos

Principais autores:	Elisabeth A vanErp, Anke J Lakerveld, Erik deGraaf, Mads D Larsen, Rutger M Schepp, Agnes L Hipgrave Ederveen, Inge ML Ahout, Cornelis AM deHaan, Manfred Wuhrer, Willem Luytjes, Gerben Ferwerda, Gestur Vidarsson, Puck B vanKasteren
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2020-01-01
coleção:	Clinical & Translational Immunology
Assuntos:	antibody‐dependent cell‐mediated cytotoxicity Fc‐mediated effector functions fucosylation interferon‐gamma NK cell respiratory syncytial virus
Acesso em linha:	https://doi.org/10.1002/cti2.1112
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