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Presaging critical residues in protein interfaces-web server (PCRPi-W): a web server to chart hot spots in protein interfaces.

It is well established that only a portion of residues that mediate protein-protein interactions (PPIs), the so-called hot spot, contributes the most to the total binding energy, and thus its identification is an important and relevant question that has clear applications in drug discovery and prote...

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Autori principali: Joan Segura Mora, Salam A Assi, Narcis Fernandez-Fuentes
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2010-08-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC2925954?pdf=render
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