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Microfilariae Trigger Eosinophil Extracellular DNA Traps in a Dectin-1-Dependent Manner

Summary: Eosinophils mediate protection against filarial nematodes. Our results demonstrate that eosinophil extracellular traps (EETosis) are induced by microfilariae and infective L3 larvae of Litomosoides sigmodontis. These extracellular DNA traps inhibit microfilariae motility in a DNA- and conta...

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Autori principali: Alexandra Ehrens, Benjamin Lenz, Anna-Lena Neumann, Samuela Giarrizzo, Julia Jennifer Reichwald, Stefan Julian Frohberger, Wiebke Stamminger, Benedikt Christian Buerfent, Frédéric Fercoq, Coralie Martin, Daniel Kulke, Achim Hoerauf, Marc Peter Hübner
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2021-01-01
Serie:Cell Reports
Soggetti:
filaria
extracellular DNA traps
eosinophils
microfilaria
L3 larva
ETosis
Accesso online:http://www.sciencedirect.com/science/article/pii/S2211124720316107
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