NGS identifies novel HLA-DQA1 and DPB1 associations with aplastic anemia in the Kazakhstani population

BackgroundAplastic anemia (AA) is a rare but serious blood disorder defined by autoimmune-driven destruction of bone marrow stem and progenitor cells. HLA polymorphisms are AA risk factors, with population-specific associations influencing disease susceptibility, treatment response, and transplant o...

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主要な著者:	Aida Turganbekova, Zhulduz Zhanzakova, Perizat Kanabekova, Dana Baimukasheva, Zhazira Saduakas, Didara Khamitova, Saniya Abdrakhmanova, Zhaksylyk Masalimov, Wassim Y. Almawi
フォーマット:	Artigo
言語:	Inglês
出版事項:	Frontiers Media S.A. 2026-02-01
シリーズ:	Frontiers in Immunology
主題:	aplastic anemia DPB1 alleles DQA1 alleles HLA polymorphisms next-generation sequencing
オンライン･アクセス:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1752687/full
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