NGS identifies novel HLA-DQA1 and DPB1 associations with aplastic anemia in the Kazakhstani population

BackgroundAplastic anemia (AA) is a rare but serious blood disorder defined by autoimmune-driven destruction of bone marrow stem and progenitor cells. HLA polymorphisms are AA risk factors, with population-specific associations influencing disease susceptibility, treatment response, and transplant o...

Descripció completa

Dades bibliogràfiques

Autors principals:	Aida Turganbekova, Zhulduz Zhanzakova, Perizat Kanabekova, Dana Baimukasheva, Zhazira Saduakas, Didara Khamitova, Saniya Abdrakhmanova, Zhaksylyk Masalimov, Wassim Y. Almawi
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2026-02-01
Col·lecció:	Frontiers in Immunology
Matèries:	aplastic anemia DPB1 alleles DQA1 alleles HLA polymorphisms next-generation sequencing
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1752687/full
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!