Xeroderma Pigmentosum Complementation Group C (XPC): Emerging Roles in Non-Dermatologic Malignancies

Xeroderma pigmentosum complementation group C (XPC) is a DNA damage recognition protein essential for initiation of global-genomic nucleotide excision repair (GG-NER). Humans carrying germline mutations in the XPC gene exhibit strong susceptibility to skin cancer due to defective removal via GG-NER...

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Autori principali:	Nawar Al Nasrallah, Benjamin M. Wiese, Catherine R. Sears
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2022-04-01
Serie:	Frontiers in Oncology
Soggetti:	nucleotide excision repair (NER) base excision repair (BER) lung cancer biomarker bladder cancer chemotherapy
Accesso online:	https://www.frontiersin.org/articles/10.3389/fonc.2022.846965/full
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