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Xeroderma Pigmentosum Complementation Group C (XPC): Emerging Roles in Non-Dermatologic Malignancies

Xeroderma pigmentosum complementation group C (XPC) is a DNA damage recognition protein essential for initiation of global-genomic nucleotide excision repair (GG-NER). Humans carrying germline mutations in the XPC gene exhibit strong susceptibility to skin cancer due to defective removal via GG-NER...

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Bibliografische gegevens
Hoofdauteurs: Nawar Al Nasrallah, Benjamin M. Wiese, Catherine R. Sears
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2022-04-01
Reeks:Frontiers in Oncology
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Online toegang:https://www.frontiersin.org/articles/10.3389/fonc.2022.846965/full
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