The soluble mannose receptor (sMR) is elevated in alcoholic liver disease and associated with disease severity, portal hypertension, and mortality in cirrhosis patients.

Hepatic macrophages (Kupffer cells) are involved in the immunopathology of alcoholic liver disease (ALD). The mannose receptor (MR, CD206), expressed primarily by macrophages, mediates endocytosis, antigen presentation and T-cell activation. A soluble form, sMR, has recently been identified in human...

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Detalhes bibliográficos

Principais autores:	Thomas Damgaard Sandahl, Sidsel Hyldgaard Støy, Tea Lund Laursen, Sidsel Rødgaard-Hansen, Holger Jon Møller, Søren Møller, Hendrik Vilstrup, Henning Grønbæk
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2017-01-01
coleção:	PLoS ONE
Acesso em linha:	http://europepmc.org/articles/PMC5728513?pdf=render
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