The soluble mannose receptor (sMR) is elevated in alcoholic liver disease and associated with disease severity, portal hypertension, and mortality in cirrhosis patients.

Hepatic macrophages (Kupffer cells) are involved in the immunopathology of alcoholic liver disease (ALD). The mannose receptor (MR, CD206), expressed primarily by macrophages, mediates endocytosis, antigen presentation and T-cell activation. A soluble form, sMR, has recently been identified in human...

Полное описание

Библиографические подробности

Главные авторы:	Thomas Damgaard Sandahl, Sidsel Hyldgaard Støy, Tea Lund Laursen, Sidsel Rødgaard-Hansen, Holger Jon Møller, Søren Møller, Hendrik Vilstrup, Henning Grønbæk
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Public Library of Science (PLoS) 2017-01-01
Серии:	PLoS ONE
Online-ссылка:	http://europepmc.org/articles/PMC5728513?pdf=render
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