Progranulin deficiency associates with postmenopausal osteoporosis via increasing ubiquitination of estrogen receptor α
Estrogen deficiency is considered the most important cause of postmenopausal osteoporosis. However, the underlying mechanism is still not completely understood. In this study, progranulin (PGRN) was isolated as a key regulator of bone mineral density in postmenopausal women through high throughput p...
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| Автори: | , , , , , , , , , , , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
KeAi Communications Co., Ltd.
2025-01-01
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| Серія: | Genes and Diseases |
| Предмети: | |
| Онлайн доступ: | http://www.sciencedirect.com/science/article/pii/S2352304224000187 |
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