Lactylation: a novel epigenetic bridge connecting metabolic reprogramming and immune dysregulation in sepsis-associated ARDS

Sepsis−associated acute respiratory distress syndrome (ARDS) is driven by metabolic reprogramming and immune dysregulation, but the molecular link between them remains unclear. Lactylation, a lactate−derived post−translational modification, couples metabolic state to transcriptional and functional o...

Full description

Bibliographic Details

Main Authors:	Linxiao Wang, Lin Liu, Yanjun Wang, Fang Wang, Xi Gao, Yinghui Li
Format:	Artigo
Language:	Inglês
Published:	Frontiers Media S.A. 2026-07-01
Series:	Frontiers in Immunology
Subjects:	acute respiratory distress syndrome epigenetics histone lactylation immune dysregulation lactylation metabolic reprogramming
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1879961/full
Tags:	Add Tag No Tags, Be the first to tag this record!