A Stepwise Algorithm for Linearly Combining Biomarkers under Youden Index Maximization

Combining multiple biomarkers to provide predictive models with a greater discriminatory ability is a discipline that has received attention in recent years. Choosing the probability threshold that corresponds to the highest combined marker accuracy is key in disease diagnosis. The Youden index is a...

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Κύριοι συγγραφείς:	Rocío Aznar-Gimeno, Luis M. Esteban, Rafael del-Hoyo-Alonso, Ángel Borque-Fernando, Gerardo Sanz
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	MDPI AG 2022-04-01
Σειρά:	Mathematics
Θέματα:	linear combination stepwise algorithm Youden index biomarkers diagnosis
Διαθέσιμο Online:	https://www.mdpi.com/2227-7390/10/8/1221
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