A Stepwise Algorithm for Linearly Combining Biomarkers under Youden Index Maximization

Combining multiple biomarkers to provide predictive models with a greater discriminatory ability is a discipline that has received attention in recent years. Choosing the probability threshold that corresponds to the highest combined marker accuracy is key in disease diagnosis. The Youden index is a...

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Principais autores:	Rocío Aznar-Gimeno, Luis M. Esteban, Rafael del-Hoyo-Alonso, Ángel Borque-Fernando, Gerardo Sanz
格式:	Artigo
語言:	Inglês
出版:	MDPI AG 2022-04-01
叢編:	Mathematics
主題:	linear combination stepwise algorithm Youden index biomarkers diagnosis
在線閱讀:	https://www.mdpi.com/2227-7390/10/8/1221
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