Irradiated Tumor Cell‐Derived Microparticles Activate Systemic Anti‐Tumor Immunity via the STING/NLRP3/GSDMD Axis in Neutrophils

ABSTRACT Radiotherapy is known to trigger immunogenic cell death and activate local anti‐tumor immune responses. However, its systemic immunomodulatory effects remain poorly understood. Here, we discovered that irradiated tumor cell‐derived microparticles (RT‐MPs) are released into the circulation a...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Yan Hu, Jiacheng Wang, Mengjie Che, Zheng Yang, Jingshu Meng, Xiao Yang, Yue Deng, Zhiyuan Zhou, Yijun Wang, Wenwen Wei, Zhanjie Zhang, Bian Wu, You Qin, Kunyu Yang, Honglin Jin, Fang Huang, Yajie Sun, Lu Wen, Chao Wan
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Wiley 2026-03-01
Цуврал:	Advanced Science
Нөхцлүүд:	extracellular vesicles, irradiated tumor cell‐derived microparticles IL‐1β, neutrophil, radiotherapy
Онлайн хандалт:	https://doi.org/10.1002/advs.202514390
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!