Decreased MFN2 activates the cGAS-STING pathway in diabetic myocardial ischaemia–reperfusion by triggering the release of mitochondrial DNA

Abstract Background The cause of aggravation of diabetic myocardial damage is yet to be elucidated; damage to mitochondrial function has been a longstanding focus of research. During diabetic myocardial ischaemia–reperfusion (MI/R), it remains unclear whether reduced mitochondrial fusion exacerbates...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Yonghong Xiong, Yan Leng, Hao Tian, Xinqi Deng, Wenyuan Li, Wei Li, Zhongyuan Xia
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2023-08-01
coleção:	Cell Communication and Signaling
Assuntos:	Diabetes Myocardial ischaemia–reperfusion Mitochondrial DNA cGAS-STING
Acesso em linha:	https://doi.org/10.1186/s12964-023-01216-y
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!