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Detection of activating mutations in liquid biopsy of Egyptian breast cancer patients using targeted next-generation sequencing: a pilot study

Abstract Background Breast cancer (BC) is the 2nd most prevalent malignancy worldwide and is the most prevalent cancer among Egyptian women. The number of newly described cancer-associated genes has grown exponentially since the emergence of next-generation sequencing (NGS) technology. We aim to ide...

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Hlavní autoři: Neemat Kassem, Hebatallah Kassem, Loay Kassem, Mohamed Hassan
Médium: Artigo
Jazyk:Inglês
Vydáno: SpringerOpen 2021-04-01
Edice:Journal of the Egyptian National Cancer Institute
Témata:
Breast cancer
Next-generation sequencing
Activating mutations
Microsatellite instability
On-line přístup:https://doi.org/10.1186/s43046-021-00067-3
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