Identifying actionable genetic mutations and microsatellite instability in liquid biopsy of colorectal cancer

Introduction: Colorectal cancer (CRC) is a molecularly diverse disorder arising from gradual accumulation of genetic and epigenetic changes giving interest in characterization of genetic alterations and microsatellite instability (MSI) for identification of new personalized therapeutic targets. Obje...

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Hauptverfasser:	Neemat M. Kassem, Mohamed G. Seadawy, Maha Gaafar, Hebatallah A. Kassem, Amira Farouk Ahmed Hussein, Enas M. Ali Rizk, Marwa A. Hassan, Riham H. AbdelAziz, Mentallah M. Abdelradi, Mostafa F. El-Hosseny, Mohamed Abdulla, Rabab Abdel Moneim
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2025-12-01
Schriftenreihe:	Journal of Genetic Engineering and Biotechnology
Schlagworte:	Colorectal cancer Next generation sequencing Activating mutations Microsatellite instability Gut microbiota & protists infections
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S1687157X25001246
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