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Short PDE4 Isoforms as Drug Targets in Disease

The second messenger, cyclic adenosine monophosphate (cAMP), is a master regulator of signal transduction that maintains cell homeostasis. A fine balance between cAMP synthesis by adenylyl cyclase and degradation by phosphodiesterases (PDEs) underpins receptor-specific responses. As multiple recepto...

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Detalles Bibliográficos
Principais autores: Elka Kyurkchieva, George S. Baillie
Formato: Artigo
Idioma:Inglês
Publicado: IMR Press 2023-07-01
Series:Frontiers in Bioscience-Landmark
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Acceso en liña:https://www.imrpress.com/journal/FBL/28/7/10.31083/j.fbl2807133
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